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NEW STUDY SHOWS THAT AGING HAPPENS IN BURSTS ESPECIALLY BETWEEN 40 AND 60

Physically and emotionally, ageing is challenging. In addition to greying hair and wrinkles clogging the corners of our eyes, knuckles may develop arthritis in the joints. Cognitive function may eventually deteriorate as the body loses its ability to perform previously effortless tasks. Everybody responds to ageing differently; some people embrace it, while others resist it. However, there is still much to learn about the ageing process of humans, which can help to improve health outcomes throughout life. According to a recent study that was published in the journal Nature Aging, ageing is not a linear process but rather has strong accelerations around the ages of 44 and 60.

Most people would think that as we age, our bodies would also age and change more annually. But there are times when things drastically change. The study tracked 108 volunteers who allowed researchers to examine their bodily products every few months for months or years. Oral, nasal, skin, blood, and stool samples were collected. After that, the scientists analyzed the samples to look for 135,000 different kinds of bacteria and molecules on or in them. The presence of bacteria or changes in the levels of a molecule like RNA can provide information about how our bodies respond to ageing.

Significant changes in the molecules and microorganisms under investigation suggested times of more rapid ageing. Around age 44 for the first and around age 60 for the second. Although previous research has indicated that 78 may also be an intense age, the period after 75 is less certain because the study only looked at ages 25 to 75. At first, the researchers believed that women were responsible for the data and that the sharp changes around age 44 were perimenopausal. But there are also notable changes in men.

Middle age is a period of intense ageing, even though other factors, like shifting behaviours, may also have an impact on the data. Similarly, the risk of developing certain conditions, like cardiovascular diseases, increases significantly after the age of sixty. After age 44, the body's capacity to process alcohol decreases. Additionally, metabolism drastically slows down after age 60.

"We're not merely evolving gradually. Michael Snyder of Stanford University's Center for Genomics and Personalised Medicine, who wrote the paper, stated, "There are some really dramatic changes." "It turns out that, regardless of the class of molecules you look at, the mid-40s and early 60s are periods of dramatic change."


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